گیاهان تیره کاسنی: ترکیبات شیمیایی، اثرات فارماکولوژیک و کاربردهای سنتی | ||
زیست قوم شناسی و حفاظت تنوع زیستی | ||
دوره 1، شماره 4، دی 1403، صفحه 90-113 اصل مقاله (804.38 K) | ||
نوع مقاله: مروری | ||
شناسه دیجیتال (DOI): 10.22091/ethc.2024.10336.1012 | ||
نویسندگان | ||
سید حمزه حسینی* 1؛ سید وریا حسینی2؛ مهدی محمدی3؛ مهدی احمدیوسفی4 | ||
1گروه زیست شناسی، دانشکده علوم، دانشگاه جیرفت، جیرفت، ایران. | ||
2گروه مرتع داری، دانشکده منابع طبیعی، دانشگاه تربیت مدرس، تهران، ایران. | ||
3گروه بیوتکنولوژی، دانشکده علوم محیطی، دانشگاه تحصیلات تکمیلی صنعتی و فناوری پیشرفته کرمان، ایران. | ||
4گروه زراعت، دانشکده کشاورزی، دانشگاه کشاورزی و منابع طبیعی گرگان، ایران. | ||
چکیده | ||
هدف: این پژوهش با هدف بررسی گیاهان تیره کاسنی و کاربردهای سنتی آن صورت گرفت. مواد و روشها: ابتدا فهرست 21 گونه دارویی از تیره کاسنی (Asteraceae) به عنوان بزرگترین تیره گیاهی به روش کتابخانهای تهیه گردید. سپس هر گونه گیاهی از لحاظ ترکیبات فیتوشیمیایی، فعالیت بیولوژیک ماده مؤثره، کارآزماییهای بالینی، تداخلات و عوارض جانبی گزارش شده و همچنین استفادههای سنتی به صورت مروری تا سال 2022 با استفاده از مقالات، کتب، به ویژه کتب مرجع گیاهان دارویی مورد مطالعه قرار گرفت. نتایج: ترکیبات اسانسی از نوع مونوترپنها و سزکوییترپنها به عنوان ترکیبات عمده ماده مؤثره اغلب گونهای گیاهی بودند و سزکوییترپنلاکتونها به عنوان ترکیبات شاخص ماده مؤثره گیاهان تیره کاسنی هستند. دیگر ترکیبات شامل تریترپنوئیدها و بعضاً آلکالوئیدها نیز در ماده مؤثره گیاهان این تیره شناسایی و جداسازی شدهاند. از طرفی در کنار ترکیبات فیتوشیمیایی، فعالیت بیولوژیک ماده مؤثره، استفادههای سنتی و تداخل و عوارض جانبی ماده مؤثره گیاهان دارویی تیره کاسنی نیز گزارش شده است که میتواند اطلاعات مناسبی را برای محققان و تولیدکنندگان داروهای گیاهی فراهم آورد. همچنین در مصرف و تجویز منطقی گیاهان دارویی تیره کاسنی میتواند منبع مناسبی باشد. نتیجهگیری: به طور کلی مرور منابع سنتی و مقالات گزارش شده حاکی از این است که تیره کاسنی یکی از مهمترین تیرههای گیاهی دارویی است و گیاهانی از قبیل بابونه کبیر، گل همیشهبهار و خارمریم ضمن استفاده دارویی به میزان بالا، هنوز جای مطالعه بیشتر و پتانسیل تولیدات دارویی ارزشمندی را دارند. | ||
کلیدواژهها | ||
ترکیبات فیتوشیمیایی؛ تداخلات دارویی؛ تیره کاسنی؛ گیاهان دارویی | ||
عنوان مقاله [English] | ||
Asteraceae family: phytochemical composition, pharmacological effects and traditional uses | ||
نویسندگان [English] | ||
Seyed Hamzeh Hosseini1؛ Seyed Vorya Hosseini2؛ Mehdi Mohammadi3؛ Mehdi Ahmadyousefi4 | ||
1Department of Biology, Faculty of Science, University of Jiroft, Jiroft, Iran. | ||
2Rangeland Management Department, Faculty of Natural Resources, Tarbiat Modares University, Tehran Iran. | ||
3Biotechnology Group, Department of Environmental Sciences, Graduate University of Advanced Technology and Industry, Kerman, Iran. | ||
4Agronomy Group, Faculty of Agriculture, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran. | ||
چکیده [English] | ||
Objective: the objective of this study was to investigate Asteraceae family and its traditional uses. Methods: A list of 21 medicinal plant species from Asteraceae family as the largest plant family was recorded by library method. Then, each plant was reviewed in terms of phytochemical compounds, biological activity, clinical trials, interactions, side effects and traditional uses using scientific articles, books, especially PDR for herbal medicine. Results: Essential oil compounds such as monoterpenes and sesquiterpenes were the main active ingredient compounds of most these plant species, and sesquiterpene lactones were the special active compounds of Asteraceae family. Other compounds including triterpenoids and a few alkaloids have also been identified and isolated in the active substance of plants of this family. Biological activity of the phytochemicals, the traditional uses and the interactions and side effects of the active ingredient of the medicinal plants of the Asteraceae family have also been reported, which can provide appropriate information for researchers and production of herbal medicines. Also, these findings can be a reliable reference for the logical prescription and use of the Asteraceae family medicinal plants. Conclusion: Generally, a review of traditional references and reported articles indicates that the Asteraceae family is one of the most important medicinal plant families, and plants such as T. parthenium, C. officinalis, and S. marianum, while being used medicinally, still needs further research and the potential of valuable natural products. | ||
کلیدواژهها [English] | ||
Asteraceae, Drug interactions, Medicinal plants, Phytochemical compounds | ||
مراجع | ||
Abu‑Lafi, S., Rayan, B., Kadan, S., Abu‑Lafi, M., & Rayan, A. (2019). Anticancer activity and phytochemical composition of wild Gundelia tournefortii. Oncology Letters, 17(1), 713-717. Ahamad, J. (2019). A pharmacognostic review on Artemisia absinthium. International Research Journal of Pharmacy, 10(1), 25-31. Ahmad, M., Waheed, I., Khalil-ur-Rehman, M., Niaz, U., & Hassan, S. (2007). A review on Carthamus oxycantha. Pakistan Journal of Pharmaceutical Sciences, 20(1). Al-Akhras, M.-A. H., Aljarrah, K., Al-Khateeb, H., Jaradat, A., Al-Omari, A., Al-Nasser, A., Masadeh, M. M., Amin, A., Hamza, A., & Mohammed, K. (2012). Introducing cichorium pumilum as a potential therapeutical agent against drug-induced benign breast tumor in rats. Electromagnetic Biology and Medicine, 31(4), 299-309. Al-Qura’n, S. (2010). Ethnobotanical and ecological studies of wild edible plants in Jordan. Libyan Agriculture Research Center Journal International, 1(4), 231-243. Al-Snafi, A. (2014). The Pharmacological importance and chemical constituents of Arctium Lappa. A review. International Journal for Pharmaceutical Research Scholars, 3(1-1), 663-670. Al-Snafi, A. E. (2015). Therapeutic properties of medicinal plants: a review of their antibacterial activity (part 1). International Journal of Pharmacology and Toxicology, 6(3), 137-158. Al-Snafi, A. E. (2016). Medical importance of Cichorium intybus–A review. IOSR Journal of Pharmacy, 6(3), 41-56. Aldayarov, N., Tulobaev, A., Salykov, R., Jumabekova, J., Kydyralieva, B., Omurzakova, N., Kurmanbekova, G., Imanberdieva, N., Usubaliev, B., & Borkoev, B. (2022). An ethnoveterinary study of wild medicinal plants used by the Kyrgyz farmers. Journal of Ethnopharmacology, 285, 114842. Alwahibi, L. H., Abdel-Mageed, W. M., Abdelkader, M., Bayoumi, S. A., Basudan, O. A., El-Gamal, A. A., & Bolla, K. (2016). Sesquiterpene lactones and flavonoids from Artemisia sieberi. IJPPR, 8(4), 639-644. Anvari, S., Bahaoddini, A., Moein, M., & Khosravi, A. R. (2016). The effect of hydroalcoholic extract of Achillea eriophora DC. on blood pressure of anaesthetized male rat. Excli Journal, 15, 797. Apaza Ticona, L., Hervás Povo, B., & Rumbero Sánchez, Á. (2024). Spectroscopical analysis of andean plant species with anti-inflammatory, antioxidant, and antibacterial activities. Revista Brasileira de Farmacognosia, 34(1), 135-153. Arab, H., Rahbari, S., Rassouli, A., Moslemi, M., & Khosravirad, F. (2006). Determination of artemisinin in Artemisia sieberi and anticoccidial effects of the plant extract in broiler chickens. Tropical Animal Health and Production, 38, 497-503. Asadi-Samani, M., Rafieian-Kopaei, M., & Azimi, N. (2013). Gundelia: a systematic review of medicinal and molecular perspective. Pakistan Journal of Biological Sciences: PJBS, 16(21), 1238-1247. Asghari, G., Davazdah, E. S., Hojjati, M., Valian, Z., Shakoori, A., & Asghari, M. (2013). Artemisinin Production in plant, callus and cell suspension culture of Artemisia aucheri boiss. Asghari, G., Jalali, M., & Sadoughi, E. (2012). Antimicrobial activity and chemical composition of essential oil from the seeds of Artemisia aucheri Boiss. Jundishapur Journal of Natural Pharmaceutical Products, 7(1), 11. Avallone, R., Zanoli, P., Puia, G., Kleinschnitz, M., Schreier, P., & Baraldi, M. (2000). Pharmacological profile of apigenin, a flavonoid isolated from Matricaria chamomilla. Biochemical Pharmacology, 59(11), 1387-1394. Aydin, Ç., Özcan, G. T., Turan, M., & Mammadov, R. (2016). Phenolic contents and antioxidant properties of Echinops ritro L. and E. tournefortii Jaup. Et. Spach extract. International Journal of Secondary Metabolite, 3(2), 74-81. Bahmani, M., Shirzad, H., Rafieian, S., & Rafieian-Kopaei, M. (2015). Silybum marianum: beyond hepatoprotection. Journal of Evidence-Based Complementary & Alternative Medicine, 20(4), 292-301. Băieş, M.-H., Cotuţiu, V.-D., Spînu, M., Mathe, A., Cozma-Petruț, A., Bocǎneţ, V. I., & Cozma, V. (2023). Satureja hortensis L. and Calendula officinalis L., two Romanian plants, with in vivo antiparasitic potential against digestive parasites of swine. Microorganisms, 11(12), 2980. Bayrami, Z., Hajiaghaee, R., Khalighi-Sigaroodi, F., Rahimi, R., Farzaei, M. H., Hodjat, M., Baeeri, M., Rahimifard, M., Navaei-Nigjeh, M., & Abdollahi, M. (2018). Bio-guided fractionation and isolation of active component from Tragopogon graminifolius based on its wound healing property. Journal of Ethnopharmacology, 226, 48-55. Bidgoli, R. D., Pessarakli, M., & Heshmati, G. A. (2012). Comparison of essential oils in aerial parts of Artemisia sieberi from Kashan Province of Iran. Journal of Agricultural Science and Technology. 2(3A), 392. Bitew, H., & Hymete, A. (2019). The genus Echinops: Phytochemistry and biological activities: A review. Frontiers in Pharmacology, 10, 1234. Boghozian, A., Amjad, L., & Shahanipour, K. (2014). Chemical constituents and identification of the essential oil of Artemisia Aucheri Boiss. in Iran. Advances in Environmental Biology, 2339-2344. Chakradhari, S., Perkons, I., Mišina, I., Sipeniece, E., Radziejewska-Kubzdela, E., Grygier, A., Rudzińska, M., Patel, K. S., Radzimirska-Graczyk, M., & Górnaś, P. (2020). Profiling of the bioactive components of safflower seeds and seed oil: Cultivated (Carthamus tinctorius L.) vs. wild (Carthamus oxyacantha M. Bieb.). European Food Research and Technology, 246, 449-459. Delfani, S., Mohammadrezaei-Khorramabadi, R., Abbaszadeh, S., Naghdi, N., & Shahsavari, S. (2017). Phytotherapy for Streptococcus pyogenes. Journal of Pharmaceutical Sciences and Research, 9(5), 513. Dungani, R., HPS, A. K., Aprilia, N. A. S., Sumardi, I., Aditiawati, P., Darwis, A., Karliati, T., Sulaeman, A., Rosamah, E., & Riza, M. (2017). Bionanomaterial from agricultural waste and its application. In Cellulose-Reinforced Nanofibre Composites (pp. 45-88). Elsevier. Elsharkawy, E., & Alshathly, M. (2013). Anticancer activity of Lactuca steriolla growing under dry desert condition of Northern Region in Saudi Arabia. Journal of Natural Sciences Research, 3(2), 5-18. Farzaei, M. H., Ghasemi-Niri, S. F., Abdolghafari, A. H., Baeeri, M., Khanavi, M., Navaei-Nigjeh, M., Abdollahi, M., & Rahimi, R. (2015). Biochemical and histopathological evidence on the beneficial effects of Tragopogon graminifolius in TNBS-induced colitis. Pharmaceutical Biology, 53(3), 429-436. Fleming, T. (2000). PDR for herbal medicines: from medical economics company. New Jersy: USA, 253. Ghani, A., Azizi, M., Hassanzadeh-Khayyat, M., & Pahlavanpour, A. A. (2008). Essential oil composition of Achillea eriophora, A. nobilis, A. biebersteinii and A. wilhelmsii from Iran. Journal of Essential Oil Bearing Plants, 11(5), 460-467. Gharehmatrossian, S., Popov, Y., Ghorbanli, M., & Safaeian, S. (2012). Antioxidant activities and cytotoxic effects of whole plant and isolated culture of Artemisia aucheri Boiss. Asian Journal of Pharmaceutical and Clinical Research, 5(4), 95-98. Goorani, S., Koohi, M. K., Zangeneh, A., Hosseini, F., & Zangeneh, M. (2018). Ameliorative property of the ethanolic extract of Tragopogon graminifolius DC. on carbon tetrachloride-induced hepatotoxicity in mice: A pharmacological examination. Iranian Journal of Pharmacology and Therapeutics, 16(1), 1-8. Gupta, V., Mittal, P., Bansal, P., Khokra, S. L., & Kaushik, D. (2010). Pharmacological potential of Matricaria recutita-A review. International Journal of Pharmaceutical Sciences and Drug Research, 2(1), 12-16. Hameed, I. H., Mohammed, G. J., & Kamal, S. A. (2018). A review: Uses and Pharmacological activity of Matricaria chamomilla. Indian Journal of Public Health Research and Development, 9(3), 200-205. Hosseinzadeh, L., Shokoohinia, Y., Arab, M., Allahyari, E., & Mojarrab, M. (2019). Cytotoxic and apoptogenic sesquiterpenoids from the petroleum ether extract of Artemisia aucheri aerial parts. Iranian Journal of Pharmaceutical Research: IJPR, 18(1), 391. Hussain, M., Raja, N. I., Akram, A., Iftikhar, A., Ashfaq, D., Yasmeen, F., Mazhar, R., Imran, M., & Iqbal, M. (2017). A status review on the pharmacological implications of Artemisia absinthium: A critically endangered plant. Asian Pacific Journal of Tropical Disease, 7(3), 185-192. Janbaz, K. H., Latif, M. F., Saqib, F., Imran, I., Zia-Ul-Haq, M., & De Feo, V. (2013). Pharmacological effects of Lactuca serriola L. in experimental model of gastrointestinal, respiratory, and vascular ailments. Evidence-based Complementary and Alternative Medicine, 2013. Kalkhorani, M., Hadjiakhoondi, A., Yassa, N., Amin, M., Damankash, S. B., & Moradkhani, F. (2020). Bio-guided fractionation of Centaurea bruguierana subsp. belangeriana extract based on anti-Helicobacter pylori activity. Research Journal of Pharmacognosy, 7(1), 61-67. Khan, Z. U. H., Ali, F., Khan, S. U., & Ali, I. (2011). Phytochemical study on the constituents from Cirsium arvense. Mediterranean Journal of Chemistry, 1(2), 64-69. Khanavi, M., Ahmadi, R., Rajabi, A., Jabbari Arfaee, S., Hassanzadeh, G., Khademi, R., Hadjiakhoondi, A., Beyer, C., & Sharifzadeh, M. (2012). Pharmacological and histological effects of Centaurea bruguierana ssp. belangerana on indomethacin-induced peptic ulcer in rats. Journal of Natural Medicines, 66, 343-349. Kisiel, W., & Michalska, K. (2003). Root constituents of Cichorium pumilum and rearrangements of some lactucin-like guaianolides. Zeitschrift für Naturforschung C, 58(11-12), 789-792. Kłeczek, N., Michalak, B., Malarz, J., Kiss, A. K., & Stojakowska, A. (2019). Carpesium divaricatum Sieb. & Zucc. revisited: Newly identified constituents from aerial parts of the plant and their possible contribution to the biological activity of the Plant. Molecules, 24(8), 1614. Křen, V., & Walterová, D. (2005). Silybin and silymarin-new effects and applications. Biomed Papers, 149(1), 29-41. Kumar, S. V., Sanjeev, T., Ajay, S., Kumar, S. P., & Anil, S. (2012). A review on hepatoprotective activity of medicinal plants. International Journal of Advanced Research in Pharmaceutical & Bio Sciences, 1(2), 31-39. Lee, K.-T., Kim, J.-I., Park, H.-J., Yoo, K.-O., Han, Y.-N., & Miyamoto, K.-I. (2000). Differentiation-inducing effect of magnolialide, a 1β-hydroxyeudesmanolide isolated from Cichorium intybus, on human leukemia cells. Biological and Pharmaceutical Bulletin, 23(8), 1005-1007. Lovelace, E. S., Maurice, N. J., Miller, H. W., Slichter, C. K., Harrington, R., Magaret, A., Prlic, M., De Rosa, S., & Polyak, S. J. (2017). Silymarin suppresses basal and stimulus-induced activation, exhaustion, differentiation, and inflammatory markers in primary human immune cells. PloS one, 12(2), e0171139. Maghsoodlou, M. T., Valizadeh, J., Mottaghipisheh, J., & Rahneshan, N. (2015). Evaluation of the essential oil composition and antioxidant activity of Achillea eriophora as a medicinal plant. Journal of Medicinal Herbs, 5(4), 187-192. Mahboubi, M., & Bidgoli, F. G. (2009). Biological activity of essential oil from aerial parts of Artemisia aucheri Boiss. from Iran. Herba Polonica, 55(4), 96-104. Marc, B. E. H. R. Molecular investigation of cell wall formation in hemp stem tissues (Doctoral dissertation, Université catholique de Louvain). Mekhlef, A. K., Hameed, I. H., & Khudhair, M. E. (2017). Prevalence of physical injuries on the head, neck and entire body in, Hilla, Iraq. Research Journal of Pharmacy and Technology, 10(10), 3276-3282. Mohamed, T. A., Hegazy, M.-E. F., Abd El Aty, A. A., Ghabbour, H. A., Alsaid, M. S., Shahat, A. A., & Paré, P. W. (2017). Antimicrobial sesquiterpene lactones from Artemisia sieberi. Journal of Asian Natural Products Research, 19(11), 1093-1101. Mullaicharam, A., Amaresh, N., & Balasubramanian, H. (2014). Phytochemistry and pleiotropic pharmacological properties of Calendula officinalis-A Review. Journal of Pharmacognosy and Phytochemistry, 2(4), 13-18. Nadri, S., & Mahmoudvand, H. (2021). The role of Iranian medicinal plants of the Asteraceae family in pain therapy: a systematic review. Herbal Medicines Journal (Herb Med J), 6(1), 27-35. Nahrevanian, H., Sheykhkanlooye Milan, B., Kazemi, M., Hajhosseini, R., Soleymani Mashhadi, S., & Nahrevanian, S. (2012). Antimalarial effects of Iranian flora Artemisia sieberi on Plasmodium berghei in vivo in mice and phytochemistry analysis of its herbal extracts. Malaria Research and Treatment, 2012. Nargesi, S., Moayeri, A., Ghorbani, A., Seifinejad, Y., Shirzadpour, E., & Amraei, M. (2018). The effects of Matricaria chamomilla L. hydroalcoholic extract on atherosclerotic plaques, antioxidant activity, lipid profile and inflammatory indicators in rats. Biomedical Research and Therapy, 5(10), 2752-2761. Nejadhabibvash, F., Medavadi Kia, H., Toufigh, S., Ali Mohammadyan, M., Amirfathi, G., & Panahi, S. (2017). Study of the plant growth stages effect on the color, content and composition of essential oil of Achillea wilhelmsii C. Koch. Case Study: Qushchi Ghat in West Azerbaijan province. Eco-phytochemical Journal of Medicinal Plants, 5(3), 47-64. Newall, C. A., Anderson, L. A., & Phillipson, J. D. (1996). Herbal medicines. A guide for health-care professionals. The Pharmaceutical Press. Noreen, H., Semmar, N., Farman, M., & McCullagh, J. S. (2017). Measurement of total phenolic content and antioxidant activity of aerial parts of medicinal plant Coronopus didymus. Asian Pacific Journal of Tropical Medicine, 10(8), 792-801. Omidbaigi, R. (2005). Production and processing of medicinal plants. Astan'eQods' eRazavi Publication, 3. Özaltun, B., & Daştan, T. (2019). Evaluation of antimicrobial activities and in vitro cytotoxic activities of Gundelia tournefortii L. Plant extracts. SDÜ Tıp Fakültesi Dergisi, 26(4), 436-442. Pareek, A., Suthar, M., Rathore, G. S., & Bansal, V. (2011). Feverfew (Tanacetum parthenium L.): A systematic review. Pharmacognosy Reviews, 5(9), 103. Peña-Espinoza, M., Valente, A. H., Thamsborg, S. M., Simonsen, H. T., Boas, U., Enemark, H. L., López-Muñoz, R., & Williams, A. R. (2018). Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review. Parasites & Vectors, 11, 1-14. Polyak, S. J., Morishima, C., & Hawke, R. (2008). Antiviral effects of silymarin against hepatitis C: the jury is still out. Hepatology, 48(1), 345-346. Pourianezhad, F., Tahmasebi, S., Abdusi, V., Nikfar, S., & Mirhoseini, M. (2016). Review on feverfew, a valuable medicinal plant. Journal of HerbMed Pharmacology, 5(2), 45-49. Puri, A., Khandagale, P., & Ansari, Y. (2018). A review on ethnomedicinal, pharmacological and phytochemical aspects of Sonchus oleraceus Linn. (Asteraceae). International Journal of Pharmacy and Biological Sciences, 8(3), 1-9. Raberi, V. S., Esmati, M., Bodagh, H., Ghasemi, R., Ghazal, M., Matinpour, A., & Abbasnezhad, M. (2022). The Functionality of apigenin as a novel cardioprotective nutraceutical with emphasize on regulating cardiac micro RNAs. Galen Medical Journal, 11, e2535. Ripoll, C., Schmidt, B. M., Ilic, N., Poulev, A., Dey, M., Kurmukov, A. G., & Raskin, I. (2007). Anti-inflammatory effects of a sesquiterpene lactone extract from chicory (Cichorium intybus L.) roots. Natural Product Communications, 2(7), 1934578X0700200702. Saeidnia, S., Gohari, A., Mokhber-Dezfuli, N., & Kiuchi, F. (2011). A review on phytochemistry and medicinal properties of the genus Achillea. DARU: Journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 19(3), 173. Salama, M., & Salama, S. G. (2016). Arctium lappa L. (Asteraceae); a new invasive highly specific medicinal plant growing in Egypt. Pyrex Journal of Plant and Agricultural Research, 2(2), 44-53. Seca, A. M., Grigore, A., Pinto, D. C., & Silva, A. M. (2014). The genus Inula and their metabolites: From ethnopharmacological to medicinal uses. Journal of Ethnopharmacology, 154(2), 286-310. Sessa, R. A., Bennett, M. H., Lewis, M. J., Mansfield, J. W., & Beale, M. H. (2000). Metabolite profiling of sesquiterpene lactones from Lactuca species: Major latex components are novel oxalate and sulfate conjugates of lactucin and its derivatives. Journal of Biological Chemistry, 275(35), 26877-26884. Shelef, O., Guy, O., Solowey, E., Kam, M., Degen, A. A., & Rachmilevitch, S. (2016). Domestication of plants for sustainable agriculture in drylands: Experience from the Negev Desert. Arid Land Research and Management, 30(2), 209-228. Sifton, D. W. (2000). The PDR family guide to natural medicines and healing therapies. Random House Digital, Inc. Silva, E. J., Gonçalves, E. S., Aguiar, F., Evêncio, L. B., Lyra, M. M., Coelho, M. C. O., Fraga, M. d. C. C., & Wanderley, A. G. (2007). Toxicological studies on hydroalcohol extract of Calendula officinalis L. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 21(4), 332-336. Singh, O., Khanam, Z., Misra, N., & Srivastava, M. K. (2011). Chamomile (Matricaria chamomilla L.): an overview. Pharmacognosy Reviews, 5(9), 82. Stojakowska, A., Michalska, K., Kłeczek, N., Malarz, J., & Beharav, A. (2018). Phenolics and terpenoids from a wild edible plant Lactuca orientalis (Boiss.) Boiss.: A preliminary study. Journal of Food Composition and Analysis, 69, 20-24. Tiuman, T. S., Ueda-Nakamura, T., Garcia Cortez, D. G. A. C., Dias Filho, B. P., Morgado-Díaz, J. A. S., de Souza, W., & Nakamura, C. V. (2005). Antileishmanial activity of parthenolide, a sesquiterpene lactone isolated from Tanacetum parthenium. Antimicrobial Agents and Chemotherapy, 49(1), 176-182. Tourabi, M., Ghouizi, A. E., Nouioura, G., Faiz, K., Elfatemi, H., El-Yagoubi, K., Lyoussi, B., & Derwich, E. (2024). Phenolic profile, acute and subacute oral toxicity of the aqueous extract from Moroccan Mentha longifolia L. aerial part in Swiss Albino mice model. Journal of Ethnopharmacology, 319, 117293. Umehara, K., Nakamura, M., Miyake, T., Kuroyanagi, M., & Ueno, A. (1996). Studies on differentiation inducers. VI. Lignan derivatives from Arctium fructus.(2). Chemical and Pharmaceutical Bulletin, 44(12), 2300-2304. Verma, P. K., Raina, R., Agarwal, S., & Kaur, H. (2018). Phytochemical ingredients and pharmacological potential of Calendula officinalis Linn. Pharmaceutical and Biomedical Research, 4(2), 1-17. Wu, X.-H., Hu, T.-X., Yang, W.-Q., Chen, H., Hu, H.-L., Tu, L.-H., Pan, Y.-X., & Zeng, F.-M. (2012). Effects of Eucalyptus grandis leaf litter decomposition on the growth and photosynthetic characteristics of Cichorium intybus. Ying Yong Sheng tai xue bao= The Journal of Applied Ecology, 23(1), 1-8.
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