سامانه مدیریت نشریات علمی دانشگاه قم

گائینی, محمدمهدی, بنائی فر, عبدالعلی, چمنی, نرگس. (1403). اثر 4 هفته بی‌تمرینی متعاقب 3 ماه تمرین هوازی بر سطوح سرمی TNF-α و مقاومت انسولین در مردان دیابتی نوع2. پژوهش‌های فلسفی -کلامی, 1(2), 21-38. doi: 10.22091/arsnes.2024.10657.1012
محمدمهدی گائینی; عبدالعلی بنائی فر; نرگس چمنی. "اثر 4 هفته بی‌تمرینی متعاقب 3 ماه تمرین هوازی بر سطوح سرمی TNF-α و مقاومت انسولین در مردان دیابتی نوع2". پژوهش‌های فلسفی -کلامی, 1, 2, 1403, 21-38. doi: 10.22091/arsnes.2024.10657.1012
گائینی, محمدمهدی, بنائی فر, عبدالعلی, چمنی, نرگس. (1403). 'اثر 4 هفته بی‌تمرینی متعاقب 3 ماه تمرین هوازی بر سطوح سرمی TNF-α و مقاومت انسولین در مردان دیابتی نوع2', پژوهش‌های فلسفی -کلامی, 1(2), pp. 21-38. doi: 10.22091/arsnes.2024.10657.1012
گائینی, محمدمهدی, بنائی فر, عبدالعلی, چمنی, نرگس. اثر 4 هفته بی‌تمرینی متعاقب 3 ماه تمرین هوازی بر سطوح سرمی TNF-α و مقاومت انسولین در مردان دیابتی نوع2. پژوهش‌های فلسفی -کلامی, 1403; 1(2): 21-38. doi: 10.22091/arsnes.2024.10657.1012

اثر 4 هفته بی‌تمرینی متعاقب 3 ماه تمرین هوازی بر سطوح سرمی TNF-α و مقاومت انسولین در مردان دیابتی نوع2

پژوهش های کاربردی در تغذیه ورزشی و علم تمرین
دوره 1، شماره 2، تیر 1403، صفحه 21-38    اصل مقاله (2.06 M)
نوع مقاله: مقاله پژوهشی
شناسه دیجیتال (DOI): 10.22091/arsnes.2024.10657.1012
نویسندگان
محمدمهدی گائینی1؛ عبدالعلی بنائی فر2؛ نرگس چمنی* 3
1کارشناسی ارشد، گروه علوم ورزشی، دانشگاه قم، قم، ایران.
2دانشیار، دانشکده تربیت بدنی و علوم ورزشی، واحد تهران جنوب، دانشگاه آزاد اسلامی، تهران، ایران.
3کارشناسی ارشد، گروه علوم ورزشی، دانشکده ادبیات و علوم انسانی، موسسه آموزشی عالی طلوع مهر، قم، ایران
چکیده
مقدمه: هدف این مطالعه بررسی اثر 4 هفته بی‌تمرینی متعاقب 3 ماه تمرین هوازی بر سطوح سرمی TNF-α و مقاومت انسولین در مردان دیابتی نوع 2 بود.
روش: نمونه آماری این پژوهش 24 نفر مرد مبتلا به دیابت نوع دو 30 تا 40 سال با شاخص توده بدنی 30 تا 34 بودند که داوطلبانه انتخاب و به صورت تصادفی در دو گروه کنترل (12 نفر) و گروه تجربی (12 نفر) قرار گرفتند. گروه تجربی به مدت 12 هفته، و هر هفته سه جلسه تمرین هوازی، تمرینات را با شدت 55 درصد حداکثر بیشینه شروع کرده و در پایان هفته هشتم شدت تمرینات به 75 درصد رسید. 48 ساعت قبل و بعد از اجرای پژوهش و پس از 4 هفته بی‌‌تمرینی، شاخص‌‌های آنتروپومتریکی اندازه‌‌گیری شده و همچنین با هدف اندازه‌‌گیری TNF-α، گلوکز و مقاومت انسولین در هر دوگروه درحالت 12 ساعت ناشتا مقدار 4 سی‌‌سی خون گرفته شد. جهت تجزیه و تحلیل داده‌ها از آزمون تی مستقل، و برای بررسی تغییرات بین‌‌گروهی و تحلیل درون‌‌گروهی از آنالیز واریانس تکرار مکرر به همراه آزمون تعقیبی LSD استفاده شد. سطح معنی‌‌داری p<0.05 درصد بوده و تحلیل داده‌ها با استفاده از نرم‌‌افزار SPSS نسخه 22 انجام شد.
یافته‌‌ها: نتایج نشان داد 12هفته تمرین هوازی باعث کاهش معنی‌‌دار سطوح سرمی (013/0=P) TNF-α، گلوکز ناشتا (000/0=P) و مقاومت انسولین (013/0=P) در گروه تجربی شده، و این تغییرات پس از 4 هفته بی‌‌تمرینی همچنان حفظ شد. در شاخص‌‌های آنتروپومتریکی ازجمله وزن بدن (000/0=P)، توده بدن (000/0=P) و درصد چربی بدن (000/0=P) متعاقب 12هفته تمرین هوازی مشاهده شد، این مقادیر پس از 4 هفته بی‌تمرینی‌‌حفظ شد.
نتیجه‌‌گیری: 3 ماه تمرین هوازی باعث بهبود سطوح TNF-α گلوکز ناشتا، و مقاومت انسولین و نیز کاهش معنی‌‌دار شاخص‌‌های آنتروپومتریکی در مردان دیابتی نوع 2 شد. سطوح این متغیرها پس از 4 هفته بی‌‌تمرینی، همچنان به‌‌میزان معنی‌‌داری پایین‌تر از سطوح پایه حفظ گردید.
کلیدواژه‌ها
تمرین هوازی؛ بی‌تمرینی؛ گلوکز؛ انسولین؛ دیابت نوع 2؛ سطوح سرمی TNF-α؛ مردان
عنوان مقاله [English]
The effect of 4 weeks of non-exercise followed by 3 months of aerobic exercise on TNF-α serum levels and insulin resistance in men with type 2 diabetes
نویسندگان [English]
Mohammad mahdi Gaeeni1؛ ,Abdolali Banaeifar2؛ Narges Chamani3
1Master's degree, Department of Sports Science, Qom University, Qom, Iran.
2Associate Professor, Faculty of Physical Education and Sports Sciences, South Tehran Branch, Islamic Azad University, Tehran, Iran
3Master's degree, Department of Sports Science, Faculty of Literature and Humanities, Institute of Higher Education Non-profit of Tolo Mehr, Qom, Iran
چکیده [English]
Purpose: The aim of this study was to investigate the effect of 4 weeks of non-exercise followed by 3 months of aerobic exercise on serum levels of TNF-α and insulin resistance in men with type 2 diabetes.
Method: The statistical sample of this research consisted of 24 men aged 30 to 40 with type 2 diabetes and a body mass index of 30 to 34. They were voluntarily selected and randomly divided into two groups: a control group (12 individuals) and an experimental group (12 individuals). Over a period of 12 weeks, the experimental group engaged in three sessions of aerobic training per week. The exercises began at 55% of maximum intensity and by the end of the eighth week,
the intensity had increased to 75%. Anthropometric indicators were measured 48 hours before
and after the research implementation, and after 4 weeks of non-exercise. Additionally, TNF-α, glucose, and insulin resistance were measured in both groups after fasting for 12 hours, with 4 cc of blood drawn. Data analysis involved using an independent t-test and repeated analysis of variance with LSD post hoc test to examine inter-group and intra-group changes. The significance level was set at p<0.05%, and data analysis was conducted using SPSS version 22 software.
Findings: The results showed that 12 weeks of aerobic training caused a significant decrease in serum levels of TNF-α (P=0.013), fasting glucose (P=0.000), and insulin resistance (P=0.013)
in the experimental group, and these changes were maintained after 4 weeks of non-training. Anthropometric indices such as body weight (P=0.000), body mass (P=0.000), and body fat percentage (P=0.000) decreased after 12 weeks of aerobic training, and these values were maintained after 4 weeks of non-training.
Conclusion: Three months of aerobic exercise improved TNF-α levels, fasting glucose, and insulin resistance, as well as significantly reduced anthropometric indices in men with type 2 diabetes. The levels of these variables remained significantly lower than the baseline levels after four weeks of not training.
 
 
کلیدواژه‌ها [English]
Aerobic Training, Non-Training, Glucose, Insulin, Type 2 Diabetes, TNF-α Serum Levels, Men
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آمار
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